Mix together sugar and 1 teaspoon of the pumpkin pie spice in a small bowl.
Separate dough into individual biscuits.
Flatten out biscuits, then spread about 1 tablespoon of pumpkin pie mix on top of each.
Sprinkle each biscuit with pumpkin spice-sugar mixture, then continue layering until you have 4 piles of 5 biscuits.
Stack the biscuits in a row in the loaf pan, ensuring that the sides without filling are on the ends that are touching the pan.
Bake 40-45 minutes, or until biscuits are baked through, and the loaf is deep golden brown.
Cool in pan 10 minutes, then turn loaf out of the pan onto a plate or cutting board to serve.
How to Make the Glaze:
Mix together the powdered sugar, milk, vanilla extract, and remaining pumpkin pie spice in a small bowl.
Drizzle evenly over the warm loaf, then serve immediately.
Video
Notes
I recommend storing all baked goods in the refrigerator to maintain freshness. Any leftovers will stay delicious for up to 5 days when refrigerated.You can freeze the bread as well. Wrap it tightly first in plastic wrap and then in aluminum foil. It will last up to 3 months in the freezer. Thaw overnight in the refrigerator and if desired, reheat in the microwave for 15-30 seconds until warmed through.